Graph from the Economist:

Pharma is moving to biotech. I think it is a bad move for Pfizer. If their major concern is pipeline. I think they have a better change to make their pipeline better by spending $68B on small to mid size start-ups.

Here is my solution to pfizer, you are done. You are no longer a innovative company, just accept this fact and move on. You should just be a holding company for small start up and helping them to finance clinical trials.